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Beyond the Muscle: The Emerging Science of Creatine for Brain Health

Creatine for Brain Health: 2025 Cognitive Benefits

For decades, creatine has been the "gold standard" supplement for athletes and bodybuilders looking to increase power output. However, in 2025, the conversation has shifted. Emerging research suggests that the most profound benefits of creatine might actually be happening above the neck.

The Brain is an Energy Hog

Your brain represents only 2% of your body weight but consumes about 20% of your total energy. Just like muscles, the brain uses a molecule called ATP for fuel. Creatine helps regenerate that fuel quickly during periods of high mental demand.

3 Reasons to Consider Creatine for Cognitive Support

  1. Mental Fatigue: Studies have shown that creatine supplementation can help maintain mental performance during sleep deprivation or intense "deep work" sessions.

  2. Neurological Protection: Researchers are investigating how creatine supports the brain’s resilience against oxidative stress, a key factor in long-term cognitive health.

  3. Memory and Processing: Some evidence suggests that for individuals with lower natural creatine levels (such as vegetarians or the elderly), supplementation may improve short-term memory and reasoning speeds.

How to Start

If you’re curious about adding it to your routine, the standard dose of 3-5 grams of Creatine Monohydrate daily is the most researched and cost-effective method. As always, consult with a healthcare professional before starting any new supplement regimen.

Dr. Jasper Thornton
Dr. Jasper Thornton PhD in Health Nutrition